Displaying all 25 drugs Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as Regioselective protection of hydantoins – essential for hydantoin based anti-epileptic drugs List of references Publications that cite this publication. Anticonvulsant (Hydantoin). Mechanism of Action (MOA) The primary site of Drugs, which may decrease phenytoin levels, include anticancer drugs in Anticonvulsants, Hydantoin; Selective Serotonin/Norepinephrine Reuptake Inhibitors; Nonsteroidal Anti-Inflammatory Drugs; Antispasmodic Agents, Urinary by V Kumar 2024 Cited by 12(B) Chemical structures of hydantoin, thiohydantoin, selenohydantoin, Figure 5 Hydantoin-based marketed drugs. NH. N. H. Ph. Ph. O. O. NH. N. DMDM hydantoin is a preservative and antimicrobial agent found in many personal-care products Drugs Supplements. Back. Drugs Supplements. by S Livingston 2024 Cited by 3hydantoin (Peganone), reported in 2024 by Living- ston¹12 as an effective dose of drug or combination of drugs then in effect and N 3 added in fenocin tablet drugs. Can also be synthesized benzyl hydantoin, benzylidene and so on. 2.In the chemical industry, dimethyl-substituted hydantoin is a raw material for the
drugs(T42). Poisoning by hydantoin derivatives, accidental (unintentional) (T42.0X1). T42.0X. T42.0X1. T42.0X1A. ICD-10-CM Code for Poisoning by hydantoin This method was successfully applied in the preparation of various biologically active compounds, including drug analogs and natural products. drug-like by GR Hampton 2024 Cited by 25drugs. Am J Dis Child 15, 2024. Google Scholar. Aase JM: Anticonvulsant drugs and congenital abnormalities. Am J Dis Child 18, 2024. Google Scholar. Hydantoin, imidazolidine-2,4-dione, is a non-aromatic five-membered heterocycle, which is considered a valuable, privileged scaffold in medicinal chemistry. The importance of the hydantoin scaffold in drug discovery has been reinforced by several medicines in clinical use, such as phenytoin, nitrofurantoin, and enzalutamide. Pre- and Perinatal Factors in the Etiology of Mental Retardation. Michele Kiely in Reproductive and Perinatal Epidemiology, 2024. Drugs given as medication Hydantoin (imidazolidinedione) derivatives such as nitrofurantoin are small molecules that have aroused considerable interest recently due to their low rate of bacterial resistance. However, their moderate antimicrobial activity may hamper their application hydantoin-based marketed drugs and clinical candidates. CONTENTS 1. Introduction 2. Hydantoins as Clinical Candidates and Marketed Drugs 2.1. Clinical Candidates 2.1.1. BMS- 2.1.2. GLGP-0492 2.2. Marketed Drugs 2.2.1. Phenytoin and Fosphenytoin 2.2.2. Ethotoin 2.2.3. Nilutamide 2.2.4
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